XWH - 12 - 1 - 0219 TITLE : Aspm , a Key Element in Medulloblastoma Pathogenesis and a Novel Target for Treatment

XWH - 12 - 1 - 0380 TITLE : A Novel Locomotion - based Validation Assay for Candidate Drugs Using Drosophila DYT 1 Disease

Dev124271 3921..3932

Alterations in genes that regulate brain size may contribute to both microcephaly and brain tumor formation. Here, we report that Aspm, a gene that is mutated in familial microcephaly, regulates postnatal neurogenesis in the cerebellum and supports the growth of medulloblastoma, the most common malignant pediatric brain tumor. Cerebellar granule neuron progenitors (CGNPs) express Aspm when main...

Award Number : W 81 XWH - 09 - 1 - 0154 TITLE : Novel Aptamers to Target Metastasis PRINCIPAL INVESTIGATOR

XWH - 12 - 1 - 0359 TITLE : Identification and Characterization of Novel FMRP - Associated miRNAs

XWH - 06 - 1 - 0724 TITLE : CD 4 + Th 1 HER 2 - Specific T cells as a Novel Treatment for HER 2 - Overexpressing Breast Cancer